Awesome List Updates on Mar 31, 2026

16 awesome lists updated today.

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1. Awesome Docker

Monitoring

• Docker-Sentinel (⭐16) - Automated container updates with per-container policies, rollback safety, and a real-time web dashboard. By Will-Luck.

• Wiremap (⭐1) - A self-hosted visual Docker network topology explorer with real-time log streaming, live stats, embedded terminal, and container inspection. By codeofmario.

Runtime

• Mocker (⭐135) - Docker-compatible container CLI for macOS, built on Apple's Containerization framework. By us.

Security

• Den (⭐6) - Self-hosted sandbox runtime for AI agents with Docker containers, security hardening, REST API and WebSocket support. By us.

• Grype (⭐12k) - A vulnerability scanner for container images, filesystems and SBOMs. By Anchore.

Terminal / Terminal UI

• swarmcli (⭐13) - Swarm Management at the speed of thought — with real-time log streaming, instant shell access to containers, seamless port forwarding, and on-demand secret reveal capabilities, giving you full control over your Docker Swarm without breaking your flow.

• tdocker (⭐82) - A docker ps replacement for everyday container operations by @pivovarit.

Registry / Other

• NORA (⭐111) - Lightweight multi-protocol artifact registry supporting Docker, Maven, npm, Cargo and PyPI in a single 32MB binary. Pull-through cache, Web UI, Prometheus metrics, RBAC auth.

Development Environment / Other

• HarborPilot (⭐2) - Automated multi-platform Docker image builder for embedded Linux development (RK3588, RV1126, RK3568). Features three-layer config inheritance, PORT_SLOT-based port allocation, and cross-version Ubuntu support (20.04/22.04/24.04). By potterwhite.

2. Awesome Ios Books

SwiftUI

• The SwiftUI Way by Natalia Panferova

Architecture

• SwiftUI Architecture by Mohammad Azam

3. Free for Dev

APIs, Data, and ML

• Posthook - Schedule webhooks to fire at a future time with automatic retries, delivery tracking, and failure alerting. Free plan includes 1,000 webhooks per month.

4. Awesome Neovim

Fuzzy Finder / Assembly

• willyelm/pulse.nvim (⭐25) - A single entrypoint for commands. Use prefixes to quickly access diagnostics, Git and more via pickers.

Colorscheme / Assembly

• 0x-ximon/acario.nvim (⭐11) - [TS][LSP][L/D][Lua] A port of the clean, high-contrast Doom Emacs Acario theme.

5. Awesome Polars

Official documentation

• Documentation for Rust API - Official API Reference for Rust.

• Documentation for R API - Official API Reference for R.

Polars plugins / Data Manipulation

• pl-compare - Compare Dataframes to find difference in the schemas, rows and column values by @concur1.

Polars plugins / Time series / Datetime

• functime (⭐1.2k) - Machine learning Python package built on Polars for time-series predictions by @functime-org. According to the developpers, it's the world's fastest and most feature-full machine learning forecasting library !

Polars plugins / General utilities / Performance

• polars-map (⭐6) - Polars extension that provids a Map extension type and functions by @hafaio.

Polars plugins / Statistics / Analytics

• polars_kde (⭐2) - Polars plugin for kernel density estimation by @schemaitat.

Polars plugins / Miscellaneous

• immunum-polars (⭐25) - high-performance plugin for antibody segmentation and numbering, with up to 1,000,000 antibodies per second on 48-core CPU machine.

Rust / Miscellaneous

• polars for Rust (⭐38k) - Rust polars crate to use polars DataFrame with Rust.

Tutorials & workshops / Miscellaneous

• Rust Polars: Unlocking High-Performance Data Analysis — Part 1 - First part of an article that explores the world of Rust’s Polars and explain some basic concepts of Polars such as Series by @wiseaidev. Code used is available on Github here (⭐458).

• Fast String Processing with Polars — Scam Emails Dataset - A tutorial using Polars to implement a text processing pipeline process by @AntonsRuberts. Code used is available on Github here (⭐69).

• Data Pipelines with Polars: Step-by-Step Guide - A tutorial that explains how to build data pipelines with Polars by @AntonsRuberts. Code used is available on Github here (⭐69).

• Introduction course that introduces the concept of DataFrame (⭐0) with Polars and Python. It also proposes some corrected exercices by @TLouf.

Blog posts / Miscellaneous

• Why Polars uses less memory than Pandas - A blog post by Itamar Turner-Trauring detailing some techniques to opptimize Pandas memory usage and see how Polars can provide an answer in some cases.

• 7 Easy Steps To Switch From Pandas to Lightning Fast Polars And Never Return - A cheat sheet blog post of the most common Pandas operations translated into Polars by @BexTuychiev.

• Using Polars Plugins for a 14x Speed Boost with Rust - A blog post thats shows the use of Polars plugin system for Rust from some concrete examples by @ngriffiths13.

• Anatomy of a Polars Query: A Syntax Comparison of Polars vs SQL - A post that compares Polars syntax to SQL by @bfeif.

• Pandas vs. Polars — Time to Switch? - A blog post that compares Polars to Pandas in a series of 4 benchmarks performed on a csv file with 11 million rows by @daradecic.

• Case Study Comparing Pandas and Polars with 1 Million Rows Data - An blog post that compares benchmarking scores with the Independent samples t-test and Welch’s t-test using Python.

• Build a Decision Tree in Polars from Scratch - A post that explains how to build a decision tree with Polars by @tocab. Code used is available on Github here (⭐6).

6. Awesome Go

DevOps Tools / Libraries for creating HTTP middlewares

• aws-doctor (⭐419) - Diagnose AWS costs, detect idle resources, and optimize cloud spending directly from your terminal 🩺 ☁️.

• kepfi (⭐11) - A smart alternative to rm with a recovery bin and storage tracking.

7. Awesome Python

Data Validation

• voluptuous (⭐1.8k) - A Python data validation library primarily intended for validating data from untrusted sources.

8. Awesome Mac

AI Tools / Other Tools

• Atomic Chat (⭐566) - Open-source AI chat client for local and cloud models with MCP support.

• ClawdHome - Manage multiple isolated OpenClaw gateway instances from one control panel.

Utilities / Window Management

• StreamWindow - 3D window manager with intuitive views and fluid transitions.

Utilities / Quality of Life Improvements

• Dimly - Control brightness across mixed monitor setups from one menu bar app.

9. Awesome Computational Biology

Compound

• DrugTargetCommons — Community platform for curating and integrating experimental bioactivity data across drugs and targets.

Protein

• UniRef — Non-redundant sequence database clustering UniProtKB entries at multiple sequence identity thresholds.

• InterPro — Protein families, domains, and functional sites database integrating 14 member databases including Pfam and PROSITE.

• Pfam — Database of protein families described by multiple sequence alignments and hidden Markov models.

• NeXtProt — Expert knowledge base on human proteins with deep functional annotation, complementary to UniProt.

Genome

• ROADMAP Epigenomics — Reference epigenome maps for 111 primary human cell types and tissues, including histone modifications, chromatin accessibility, and DNA methylation.

• FANTOM5 — Functional annotation of mammalian genome; comprehensive atlas of active enhancers, promoters, and transcription start sites across human and mouse cell types.

Disease

• Open Targets Platform — Systematic target identification and prioritization platform integrating genetics, genomics, and drug data for drug discovery.

• Human Phenotype Ontology (HPO) — Standardized vocabulary of phenotypic abnormalities in human disease, linking genes, variants, and clinical features.

• DISEASES — Gene–disease association database integrating evidence from text mining, curated databases, and experimental data.

Chemical-Protein Interaction

• Davis kinase inhibitors DB — Experimental kinase inhibitor binding affinity dataset for protein–ligand interaction research.

• Kinase Inhibitor Bioactivity Data (KIBA) — Integrated bioactivity scores for kinase inhibitors combining Ki, Kd, and IC50 measurements.

Gene Regulatory Network

• TRRUST — Manually curated database of human and mouse transcriptional regulatory interactions between transcription factors and their target genes.

• RegNetwork — Database of gene regulatory networks covering transcription factor–target gene and miRNA–gene interaction data across multiple species.

• miRBase — Reference repository for microRNA gene annotations, sequences, and experimentally validated targets.

Benchmarks & Datasets

• PK-DB — Open database of experimental pharmacokinetics (PK) and ADME data from clinical and preclinical studies.

Preprocessing Tools

• STAR (⭐2.2k) — Ultrafast universal RNA-seq aligner with support for spliced alignment and single-cell quantification via STARsolo.

• kallisto — Near-optimal RNA-seq quantification using pseudoalignment for fast transcript abundance estimation.

• Harmony (⭐635) — Fast and scalable integration of single-cell data across datasets, conditions, technologies, and species.

• Monocle3 — Single-cell trajectory analysis tool for learning developmental trajectories and ordering cells in pseudotime.

• CellChat (⭐776) — Inference and analysis of cell-cell communication ligand-receptor networks from single-cell transcriptomics data.

• SCENIC (⭐481) — Single-cell regulatory network inference and clustering linking transcription factors to co-expressed gene modules.

• DoubletFinder (⭐540) — Machine learning approach for detecting multiplet (doublet) artifacts in single-cell RNA-seq data.

Drug Response Prediction

• TGSA (⭐23) — Tumor gene set and attention-based model leveraging biological pathway knowledge for drug response prediction.

• HiDRA — Hierarchical network model incorporating gene and pathway-level information for cancer drug response prediction.

Molecular Generation

• JTVAE (⭐555) — Junction tree variational autoencoder for molecular graph generation that guarantees chemical validity via a hierarchical tree decomposition.

LLM for Biology

• MolT5 (⭐192) — Language model for molecular tasks bridging text and SMILES, enabling molecule captioning and text-driven molecule generation.

• ChatDrug (⭐161) — LLM-based conversational pipeline for drug discovery, using natural language prompts for iterative drug editing and optimization.

Protein Foundation Models / Pre-trained Embedding

• ProtTrans (⭐1.3k) — Suite of protein language models (ProtBERT, ProtT5, ProtXLNet) trained on billions of protein sequences from UniRef and BFD.

• ProGen2 (⭐697) — Protein language model trained on diverse protein families for sequence generation and fitness prediction.

• Ankh (⭐246) — Efficient protein language model optimized for downstream prediction tasks including secondary structure, localization, and function annotation.

Genomics Foundation Models / Protein Structure Prediction and Design

• DeepSEA — Deep learning framework for predicting chromatin effects of sequence alterations with single-nucleotide sensitivity across thousands of chromatin features.

• Sei (⭐113) — Sequence-to-function framework learning a genome-wide regulatory activity code from DNA sequences for variant effect prediction.

• GPN (Genomic Pre-trained Network) (⭐338) — Masked language model for DNA sequences enabling zero-shot variant effect prediction without requiring functional annotations.

10. Awesome Rest

Documentation / Symfony2

• Sourcey - Open source documentation platform for OpenAPI specs and markdown. Static HTML output.

11. Awesome Game Engine Dev

Tools / Software / AI Assistants

• 💸 Rosebud AI - Vibe coding platform for creating 3D games and interactive web apps with AI.

Open Source Games / C++

• 🔒 GemRB (⭐1.2k) - Open-source implementation of Bioware's Infinity Engine.

12. Awesome Cli Apps

Productivity / Note Taking and Lists

• kanban (⭐90) - Keyboard-driven project management tool inspired by lazygit.

AI / Agents

• InkOS (⭐5.2k) - Novel-writing agent.

13. Awesome WSL

WSL Tools / Terminals

• Yaw - A cross-platform terminal that auto-detects WSL along with PowerShell, CMD, and Git Bash on Windows.

14. Awesome Mysql

Development

• cover_me (⭐3) - code coverage tool for mysql stored procedures and functions

15. Awesome Ai in Finance

Agents

• ProfitPlay Agent Arena (⭐6) - Open prediction market arena where AI agents compete in real-time BTC/ETH/SOL prediction games. Python and Node.js SDKs, 9 live markets, REST + WebSocket APIs.

Data Sources / Crypto Currencies

• PreReason - Pre-analyzed financial market briefings optimized for AI agent consumption. 17 briefings covering BTC on-chain, macro (Fed balance sheet, M2, Treasury yields), and cross-asset correlations. Returns regime classification, trend signals, and confidence scores in markdown.

Research Tools / Prediction Markets

• CRNG (⭐5) - Contingency RNG, generates random numbers with real market fat tails (K=5-220) and volatility clustering. Matches 86% of real market metrics vs 14% for NumPy. Includes regime detector.

Others / Plugins

• Hindsight - State-of-the-art long-term memory for AI agents by Vectorize. Open source, self-hostable, with integrations for LangChain, CrewAI, MCP, and more. Gives financial trading agents persistent memory across sessions.

16. Awesome Datascience

Podcasts / Book Deals (Affiliated)

• Chain of Thought

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